Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0C4NY
|
||||
| Former ID |
DIB013211
|
||||
| Drug Name |
Promestriene
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Acne vulgaris [ICD9: 706.1; ICD10:L70.0] | Approved | [551871] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H32O2
|
||||
| Canonical SMILES |
CCCOc1ccc2[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CCc2c1)O<br />C
|
||||
| InChI |
1S/C22H32O2/c1-4-13-24-16-6-8-17-15(14-16)5-7-19-18(17)11-12-22(2)20(19)9-10-21(22)23-3/h6,8,14,18-21H,4-5,7,9-13H2,1-3H3/t18-,19-,20+,21+,22+/m1/s1
|
||||
| InChIKey |
IUWKNLFTJBHTSD-AANPDWTMSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Modulator | [532496], [551871] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.