Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0C0KP
|
||||
| Former ID |
DIB008734
|
||||
| Drug Name |
AllerB
|
||||
| Indication | Allergy [ICD9: 995.3; ICD10:T78.4] | Phase 2b | [1] | ||
| Company |
Anergis SA
|
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| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Inhibitor | [2] | |
| BioCyc Pathway | Phospholipases | ||||
| KEGG Pathway | Glycerophospholipid metabolism | ||||
| Ether lipid metabolism | |||||
| Arachidonic acid metabolism | |||||
| Linoleic acid metabolism | |||||
| alpha-Linolenic acid metabolism | |||||
| Metabolic pathways | |||||
| Ras signaling pathway | |||||
| Vascular smooth muscle contraction | |||||
| Pancreatic secretion | |||||
| Fat digestion and absorption | |||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| Reactome | Acyl chain remodelling of PC | ||||
| Acyl chain remodelling of PE | |||||
| Acyl chain remodelling of PI | |||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
| REF 1 | Clinical pipeline report, company report or official report of Anergis SA. | ||||
| REF 2 | Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom. J Allergy Clin Immunol. 1998 Jun;101(6 Pt 1):747-54. | ||||
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