TTD | Drug: D0B2YN

Drug General Information
Drug ID	D0B2YN
Former ID	DNC013547
Drug Name	1-[(cyclohexylamino)ethyl]-1,1-bisphosphonicacid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529229]
Structure		Download 2D MOL 3D MOL
Formula	C8H19NO6P2
Canonical SMILES	C1CCC(CC1)NCC(P(=O)(O)O)P(=O)(O)O
InChI	1S/C8H19NO6P2/c10-16(11,12)8(17(13,14)15)6-9-7-4-2-1-3-5-7/h7-9H,1-6H2,(H2,10,11,12)(H2,13,14,15)
InChIKey	OAHUDYBQKIUBMC-UHFFFAOYSA-N
PubChem Compound ID	21803454
Target and Pathway
Target(s)	Farnesyl pyrophosphatesynthetase	Target Info	Inhibitor	[529229]
KEGG Pathway	Terpenoid backbone biosynthesis
	Metabolic pathways
	Biosynthesis of antibiotics
	Influenza A
	HTLV-I infection
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
Reactome	Activation of gene expression by SREBF (SREBP)
WikiPathways	Activation of Gene Expression by SREBP (SREBF)
	SREBP signalling
	Cholesterol Biosynthesis
References
Ref 529229	Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. Epub 2007 Dec 10.Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.
Ref 529229	Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. Epub 2007 Dec 10.Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.

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Drug Information