Drug General Information
Drug ID	D0B0EL
Former ID	DIB018859
Drug Name	AP18
Synonyms	AP-18; AP 18
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[467479]
Structure		Download 2D MOL 3D MOL
Formula	C11H12ClNO
InChI	InChI=1S/C11H12ClNO/c1-8(9(2)13-14)7-10-3-5-11(12)6-4-10/h3-7,14H,1-2H3/b8-7+,13-9+
InChIKey	MHTJEUOFLVQMCL-NJHPPEEMSA-N
PubChem Compound ID	9584673
PubChem Substance ID	3285917, 24002902, 26529799, 44721401, 51644901, 81047788, 89760918, 92258784, 103716547, 124642358, 134347481, 135697957, 138542248, 237610628, 241376367, 252157169
Target and Pathway
Target(s)	Transient receptor potential cation channel subfamily A member 1	Target Info	Blocker (channel blocker)	[529224]
KEGG Pathway	Inflammatory mediator regulation of TRP channels
Reactome	TRP channels
References
Ref 467479	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4134).
Ref 529224	A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain. 2007 Dec 17;3:40.

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