Drug Information

Drug General Information
Drug ID
D0AP9T
Former ID
DAP000451
Drug Name
Cefotetan
Synonyms
Cefotetanum; Apatef (TN); Cefotan (TN); Cefotetan (JP15/USP/INN); (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid; (6R,7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7S)-7-[[4-(1-amino-3-hydroxy-1,3-dioxopropan-2-ylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7beta-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [536361]
Therapeutic Class
Antibiotics
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL
Formula
C17H17N7O8S4
Canonical SMILES
CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)C4SC(=C(C(=O)N)C(=<br />O)O)S4)OC)SC2)C(=O)O
InChI
1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/t13?,15-,17+/m1/s1
InChIKey
SRZNHPXWXCNNDU-RHBCBLIFSA-N
CAS Number
CAS 69712-56-7
PubChem Compound ID
53025
PubChem Substance ID
9103, 7847326, 7978881, 11051543, 11466501, 11467621, 11486281, 15359621, 34717168, 46506572, 48020449, 48020450, 48095951, 48244839, 48415722, 49699096, 50124222, 50186741, 56463651, 57313480, 92125572, 92719732, 93302793, 93374658, 93578304, 103594731, 103914470, 104301116, 121363243, 124766176, 124800749, 126628099, 136199027, 137156467, 137249718, 141754331, 144204232, 152035519, 162176887, 162258056, 163409419, 164788214, 175611876, 179116605, 184545873, 184546368, 185985468, 196378900, 226443050, 241122609
SuperDrug ATC ID
J01DC05
SuperDrug CAS ID
cas=069712567
Target and Pathway
Target(s) DNA Target Info Binder [536418]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 536418In-vitro profile of a new beta-lactam, ceftobiprole, with activity against methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect. 2007 Jun;13 Suppl 2:17-24.

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