Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0A7JH
|
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| Former ID |
DIB004285
|
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| Drug Name |
WY-50295-tromethamine
|
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| Synonyms |
WY-50295T; Wy-49232
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Phase 2 | [1] | ||
| Company |
Wyeth-Ayerst Pharmaceuticals Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C27H30N2O6
|
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| Canonical SMILES |
n1c2c(ccc1COc1cc3c(cc([C@@H](C(=O)O)C)cc3)cc1)cccc2
|
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| CAS Number |
CAS 123016-21-7
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | WY-50295 tromethamine: a 5-lipoxygenase inhibitor without activity in human whole blood. Prostaglandins Leukot Essent Fatty Acids. 1999 Jan;60(1):31-41. | ||||
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