Drug Information
Drug General Information | |||||
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Drug ID |
D0A5SE
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Former ID |
DAP001444
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Drug Name |
Febuxostat
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Synonyms |
Adenuric; TEI; Uloric; Febuxostat [USAN]; S1547; TMX 67; Tei 6720; TMX-67; Tei-6720; Uloric (TN); Febuxostat (JAN/USAN/INN); TMX-67, Adenuric, Uloric, Febuxostat; 111GE013; 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID; 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid;2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid; 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
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Drug Type |
Small molecular drug
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Company |
Takeda
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Structure |
Download2D MOL |
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Formula |
C16H16N2O3S
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InChI |
InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
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InChIKey |
BQSJTQLCZDPROO-UHFFFAOYSA-N
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CAS Number |
CAS 144060-53-7
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PubChem Compound ID | |||||
PubChem Substance ID |
827254, 4484625, 7848269, 7890737, 10243499, 12014717, 14899120, 29311812, 46506708, 50064429, 53197612, 57344764, 92719385, 93307960, 99431926, 103765728, 104142020, 104253203, 104381153, 118047349, 119526879, 121362144, 124757329, 124893781, 125001903, 125164133, 125645402, 126620851, 126652673, 126667078, 127554532, 134338644, 135089359, 135565727, 135692175, 135697551, 135723459, 136367945, 136920430, 137171680, 141631602, 144075735, 144115972, 144206555, 151981114, 152227348, 152258563, 152344198, 160647398, 160813538
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SuperDrug ATC ID |
M04AA03
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Target and Pathway | |||||
Target(s) | Xanthine dehydrogenase/oxidase | Target Info | Inhibitor | [530677], [551717] | |
PANTHER Pathway | Adenine and hypoxanthine salvage pathway | ||||
Purine metabolism | |||||
PathWhiz Pathway | Caffeine Metabolism | ||||
Purine Metabolism | |||||
Reactome | Purine catabolism | ||||
References | |||||
Ref 530677 | Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92. | ||||
Ref 541899 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6817). |
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