Drug Information
Drug General Information | |||||
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Drug ID |
D0A5MI
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Former ID |
DIB016280
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Drug Name |
LANIQUIDAR
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Synonyms |
R-101933; Laniquidar < Prop INN >; 11-[1-[2-[4-(2-Quinolylmethoxy)phenyl]ethyl]piperidin-4-ylidene]-6,11-dihydro-5H-imidazo[2,1-b][3]benzazepine-3-carboxylic acid methyl ester
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Drug Type |
Small molecular drug
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Discontinued in Phase 2 | [521501] | ||
Structure |
Download2D MOL |
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Formula |
C37H36N4O3
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Canonical SMILES |
COC(=O)c1cnc2C(=C3CCN(CCc4ccc(OCc5ccc6ccccc6n5)cc4)CC3)<br />c7ccccc7CCn12
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InChI |
1S/C37H36N4O3/c1-43-37(42)34-24-38-36-35(32-8-4-2-6-27(32)19-23-41(34)36)29-17-21-40(22-18-29)20-16-26-10-14-31(15-11-26)44-25-30-13-12-28-7-3-5-9-33(28)39-30/h2-15,24H,16-23,25H2,1H3
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InChIKey |
TULGGJGJQXESOO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Multidrug resistance protein 3 | Target Info | Modulator | [530287] | |
KEGG Pathway | ABC transporters | ||||
Bile secretion | |||||
References |
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