Drug General Information
Drug ID
D0A4XJ
Former ID
DNC001386
Drug Name
SU5402
Drug Type
Small molecular drug
Indication Multiple myeloma [ICD9: 203; ICD10:C90] Investigative [537114]
Company
Sugen Inc
Structure
Download
2D MOL

3D MOL

Formula
C17H16N2O3
Canonical SMILES
CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
InChI
1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
InChIKey
JNDVEAXZWJIOKB-JYRVWZFOSA-N
CAS Number
CAS 215543-92-3
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) FGF-3 receptor Target Info Inhibitor [537114]
KEGG Pathway MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
MicroRNAs in cancer
Bladder cancer
Central carbon metabolism in cancer
PANTHER Pathway FGF signaling pathway
Reactome FGFR3 mutant receptor activation
WikiPathways Regulation of Actin Cytoskeleton
Endochondral Ossification
Bladder Cancer
Neural Crest Differentiation
Signaling by FGFR
References
Ref 537114Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
Ref 537114Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.

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