Drug Information

Drug General Information
Drug ID
D0A0FY
Former ID
DNC009959
Drug Name
N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530402]
Structure
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2D MOL

3D MOL
Formula
C14H13NO5S
Canonical SMILES
COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2C(=O)NO
InChI
1S/C14H13NO5S/c1-20-10-6-8-11(9-7-10)21(18,19)13-5-3-2-4-12(13)14(16)15-17/h2-9,17H,1H3,(H,15,16)
InChIKey
QPFIKHZWPMXTRS-UHFFFAOYSA-N
PubChem Compound ID
44479457
Target and Pathway
Target(s) MMP-12 Target Info Inhibitor [530402]
NetPath Pathway IL1 Signaling Pathway
IL5 Signaling Pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
WikiPathways TGF beta Signaling Pathway
Degradation of collagen
Matrix Metalloproteinases
References
Ref 530402J Med Chem. 2009 Oct 22;52(20):6347-61.Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors.
Ref 530402J Med Chem. 2009 Oct 22;52(20):6347-61.Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors.

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