Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09XVQ
|
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| Former ID |
DIB013339
|
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| Drug Name |
PT-14
|
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| Synonyms |
Erectide; PT-14 (transmucosal); PT-14 (transmucosal), Palatin/TheraTech
|
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| Indication | Erectile dysfunction [ICD9: 302.72, 607.84; ICD10:F52.2, N48.4] | Discontinued in Phase 2 | [1] | ||
| Company |
Competitive Technologies Inc
|
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| Structure |
|
Download2D MOL |
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| Target and Pathway | |||||
| Target(s) | Melanocortin-4 receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | Syndecan-3-mediated signaling events | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010143) | ||||
| REF 2 | The protective effects of the melanocortin receptor (MCR) agonist, melanotan-II (MTII), against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice. Neuropeptides. 2014 Feb;48(1):47-51. | ||||
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