TTD | Drug: D09XLT

Drug General Information
Drug ID	D09XLT
Former ID	DIB020978
Drug Name	SQ 26655
Synonyms	SQ-26,655; SQ-26655
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541319]
Structure		Download 2D MOL
Formula	C21H34O4
InChI	InChI=1S/C21H34O4/c1-2-3-6-9-17(22)13-12-16-14-18-15-20(25-18)19(16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18-,19+,20-/m0/s1
InChIKey	HAJUMEFPOWPAQL-IGUVKOCZSA-N
PubChem Compound ID	73755172
PubChem Substance ID	178102691
Target and Pathway
Target(s)	Thromboxane A2 receptor	Target Info	Agonist	[533502]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	Prostanoid ligand receptors
	G alpha (q) signalling events
	G alpha (12/13) signalling events
	Thromboxane signalling through TP receptor
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541319	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6070).
Ref 533502	Synthesis and in vitro pharmacology of 7-oxabicyclo[2.2.1]heptane analogues of thromboxane A2/PGH2. J Med Chem. 1985 Nov;28(11):1580-90.

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Drug Information