Drug General Information
Drug ID
D09XGK
Former ID
DIB004775
Drug Name
Testetrol
Synonyms
Testetrol (oral, hypogonadism); T2 (oral, hypogonadism), Pantarhei; Testetrol (oral, hypogonadism), Pantarhei; Testosterone agonist (oral, hypogonadism), Pantarhei
Indication Hypogonadism [ICD9: 257.2; ICD10:E23.0, E28.3, E29.1] Investigative [525360]
Company
Pantarhei Bioscience BV
Structure
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2D MOL

3D MOL

Canonical SMILES
[C@@]12(C(=CC(=O)CC2)CC[C@@H]2[C@@H]1CC[C@]1([C@H]2C(C[<br />C@@H]1O)O)C)C
Target and Pathway
Target(s) Androgen receptor Target Info Agonist [525360]
KEGG Pathway Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 525360Estetrol review: profile and potential clinical applications. Climacteric. 2008;11 Suppl 1:47-58.
Ref 525360Estetrol review: profile and potential clinical applications. Climacteric. 2008;11 Suppl 1:47-58.

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