Drug Information
Drug General Information | |||||
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Drug ID |
D09UEM
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Former ID |
DIB020356
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Drug Name |
minodronic acid
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Synonyms |
YH 529; ONO 5920; BPH 261
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540148] | ||
Structure |
Download2D MOL |
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Formula |
C9H12N2O7P2
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InChI |
InChI=1S/C9H12N2O7P2/c12-9(19(13,14)15,20(16,17)18)5-7-6-10-8-3-1-2-4-11(7)8/h1-4,6,12H,5H2,(H2,13,14,15)(H2,16,17,18)
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InChIKey |
VMMKGHQPQIEGSQ-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
7843852, 10242764, 12014461, 14874799, 29196193, 29196330, 29309444, 48426327, 53837734, 56374449, 57343615, 75971565, 87457604, 93309669, 99375738, 103314069, 104374011, 124894544, 125823092, 126651847, 126666053, 129496050, 131302852, 135268217, 135649663, 137084388, 141698785, 144206806, 151995601, 160650211, 160655146, 162205070, 162222716, 163416705, 164777754, 164779842, 164779843, 171578885, 175438067, 179322955, 184547763, 186024269, 196109800, 198979870, 206246374, 223589663, 223662192, 224339905, 226511683, 249828272
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Target and Pathway | |||||
Target(s) | Geranyltranstransferase | Target Info | Inhibitor | [529700] | |
Farnesyl pyrophosphatesynthetase | Target Info | Inhibitor | [530855] | ||
PANTHER Pathway | Cholesterol biosynthesis | ||||
PathWhiz Pathway | Steroid BiosynthesisPW000050:Steroid Biosynthesis | ||||
References | |||||
Ref 529700 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. J Med Chem. 2008 Sep 25;51(18):5594-607. | ||||
Ref 530855 | Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid. J Med Chem. 2010 May 13;53(9):3454-64. |
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