TTD | Drug: D09TED

Drug General Information
Drug ID	D09TED
Former ID	DNC012620
Drug Name	L-162234
Drug Type	Small molecular drug
Indication	Discovery agent		Terminated	[545499]
Structure		Download 2D MOL 3D MOL
Formula	C31H33F3N4O5S
Canonical SMILES	CCCCC1=NN(C(=O)N1CC2=CC=C(C=C2)C3=CC=CC=C3S(=O)(=O)NC(=<br />O)OC(C)(C)C)C4=CC=CC=C4C(F)(F)F
InChI	1S/C31H33F3N4O5S/c1-5-6-15-27-35-38(25-13-9-8-12-24(25)31(32,33)34)29(40)37(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)44(41,42)36-28(39)43-30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H,36,39)
InChIKey	IVFMKMCSJZZCKV-UHFFFAOYSA-N
PubChem Compound ID	9830680
Target and Pathway
Target(s)	Type-2 angiotensin II receptor	Target Info	Inhibitor	[525772]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Adrenergic signaling in cardiomyocytes
	Renin-angiotensin system
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (i) signalling events
WikiPathways	ACE Inhibitor Pathway
	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545499	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003503)
Ref 525772	J Med Chem. 2000 May 18;43(10):1993-2006.Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity.

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Drug Information