Drug General Information
Drug ID
D09QOR
Former ID
DNCL002735
Drug Name
Eniluracil
Drug Type
Small molecular drug
Indication Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78] Phase 2 [525898]
Company
Adherex Technologies
Structure
Download
2D MOL

3D MOL

Formula
C6H4N2O2
Canonical SMILES
C#CC1=CNC(=O)NC1=O
InChI
1S/C6H4N2O2/c1-2-4-3-7-6(10)8-5(4)9/h1,3H,(H2,7,8,9,10)
InChIKey
JOZGNYDSEBIJDH-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Dihydropyrimidine dehydrogenase [NADP+] Target Info Modulator [525898]
BioCyc Pathway Pyrimidine ribonucleosides degradation
Thymine degradation
Uracil degradation
KEGG Pathway Pyrimidine metabolism
beta-Alanine metabolism
Pantothenate and CoA biosynthesis
Drug metabolism - other enzymes
Metabolic pathways
PANTHER Pathway Pyrimidine Metabolism
PathWhiz Pathway Beta-Alanine Metabolism
Pyrimidine Metabolism
WikiPathways Metabolism of nucleotides
Fluoropyrimidine Activity
References
Ref 525898Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase. Expert Opin Investig Drugs. 2000 Jul;9(7):1635-49.
Ref 525898Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase. Expert Opin Investig Drugs. 2000 Jul;9(7):1635-49.

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