Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09PTR
|
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| Drug Name |
FR-900452
|
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| Synonyms |
101706-33-6; FR-900452
|
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| Drug Type |
Small molecular drug
|
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| Indication | Unspecified | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H25N3O3S
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Platelet-activating factor receptor | Target Info | Modulator | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Staphylococcus aureus infection | |||||
| NetPath Pathway | IL5 Signaling Pathway | ||||
| Leptin Signaling Pathway | |||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (q) signalling events | |||||
| Interferon gamma signaling | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Small Ligand GPCRs | |||||
| Interferon gamma signaling | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | FR-900452, a specific antagonist of platelet activating factor (PAF) produced by Streptomyces phaeofaciens.I.Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.J Antibiot (Tokyo). | ||||
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