Drug Information

Drug General Information
Drug ID
D09PNV
Former ID
DIB008030
Drug Name
KSG-504
Synonyms
4(R)-[N-(3-Methoxypropyl)-N-pentylcarbamoyl]-5-(2-naphthylsulfonyl)pentanoic acid L-arginine salt monohydrate
Drug Type
Small molecular drug
Indication Pancreatic disease [ICD10:K85-K86] Investigative [534164]
Structure
Download
2D MOL

3D MOL
Formula
C31H49N5O8S
Canonical SMILES
CCCCCN(CCCOC)C(=O)C(CCC(=O)O)CS(=O)(=O)C1=CC2=CC=CC=C2C<br />=C1.C(CC(C(=O)O)N)CN=C(N)N
InChI
1S/C25H35NO6S.C6H14N4O2/c1-3-4-7-15-26(16-8-17-32-2)25(29)22(12-14-24(27)28)19-33(30,31)23-13-11-20-9-5-6-10-21(20)18-23;7-4(5(11)12)2-1-3-10-6(8)9/h5-6,9-11,13,18,22H,3-4,7-8,12,14-17,19H2,1-2H3,(H,27,28);4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t22-;4-/m00/s1
InChIKey
TXTJVOOURRNANH-QEXBQMGZSA-N
PubChem Compound ID
132011
PubChem Substance ID
14912654, 78314097, 104376466, 135086775, 163305845
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Antagonist [534164]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 534164Effects of KSG-504, a new CCK-A receptor antagonist, on gallbladder and gastrointestinal functions. Nihon Yakurigaku Zasshi. 1996 Jan;107(1):33-44.
Ref 534164Effects of KSG-504, a new CCK-A receptor antagonist, on gallbladder and gastrointestinal functions. Nihon Yakurigaku Zasshi. 1996 Jan;107(1):33-44.

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