Drug Information

Drug General Information
Drug ID
D09OZC
Former ID
DAP001003
Drug Name
Lucanthone
Synonyms
Lucanthon; Lucanthonum; Lucantona; Miracol; Nilodin; Scapuren; Tixantone; LUCANTHONE HYDROCHLORIDE; Lucanthone monohydrochloride; Miracil D; BW 57223; CBC 900139; DR-15771; Lucanthone [INN:BAN]; Lucanthonum [INN-Latin]; Lucantona [INN-Spanish]; 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one; 1-(2-diethylaminoethylamino)-4-methylthioxanthen-9-one; 1-[[2-(Diethylamino)ethyl]amino]-4-methylthioxanthone; 1-{[2-(Diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one; 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-methyl-(9CI)
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Approved [550759]
Therapeutic Class
Anticancer Agents
Company
Spectrum
Structure
Download
2D MOL

3D MOL
Formula
C20H24N2OS
Canonical SMILES
CCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O
InChI
1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3
InChIKey
FBQPGGIHOFZRGH-UHFFFAOYSA-N
CAS Number
CAS 479-50-5
PubChem Compound ID
10180
PubChem Substance ID
13880, 605885, 6717762, 8157342, 11405383, 11447473, 15422229, 29228710, 46507260, 48416189, 50054621, 56394814, 57326018, 76348844, 103188497, 104322601, 124633672, 125824256, 126671567, 127823040, 134223140, 134338273, 134974173, 137005643, 142383948, 160967835, 179150492, 184531387, 198952423, 223670988, 226400151, 252215717
ChEBI ID
ChEBI:51052
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [536070]
References
Ref 550759Drug information of Lucanthone, 2008. eduDrugs.
Ref 536070Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70. Cell Stress Chaperones. 2005 Spring;10(1):37-45.

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