| Drug General Information |
| Drug ID |
D09LFY
|
| Former ID |
DNC000786
|
| Drug Name |
Il-8((3-73))K11R
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Target and Pathway |
| Target(s) |
High affinity interleukin-8 receptor B |
Target Info |
Agonist |
[1]
|
|---|
| High affinity interleukin-8 receptor A |
Target Info |
Agonist |
[1]
|
|
KEGG Pathway
|
Cytokine-cytokine receptor interaction
|
|
Chemokine signaling pathway
|
|
Endocytosis
|
|
Epithelial cell signaling in Helicobacter pylori infectionhsa04060:Cytokine-cytokine receptor interaction
|
|
Epithelial cell signaling in Helicobacter pylori infection
|
|
NetPath Pathway
|
TNFalpha Signaling PathwayNetPath_14:IL2 Signaling Pathway
|
|
PANTHER Pathway
|
Inflammation mediated by chemokine and cytokine signaling pathway
|
|
Interleukin signaling pathwayP00031:Inflammation mediated by chemokine and cytokine signaling pathway
|
|
Interleukin signaling pathway
|
|
Pathway Interaction Database
|
IL8- and CXCR2-mediated signaling eventsil8cxcr1_pathway:IL8- and CXCR1-mediated signaling events
|
|
Reactome
|
Chemokine receptors bind chemokines
|
|
G alpha (i) signalling eventsR-HSA-380108:Chemokine receptors bind chemokines
|
|
G alpha (i) signalling events
|
|
WikiPathways
|
GPCRs, Class A Rhodopsin-like
|
|
Peptide GPCRs
|
|
GPCR ligand binding
|
|
GPCR downstream signaling
|
|
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
|
|
Differentiation Pathway
|
|
GPCRs, Other
|
| References |
| REF 1 | Il-8((3-73))K11R is a high affinity agonist of the neutrophil CXCR1 and CXCR2. Biochem Biophys Res Commun. 2001 Aug 24;286(3):595-600. |
|---|
