Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09JYF
|
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| Former ID |
DIB011945
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| Drug Name |
Epocarbazolin-A
|
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| Synonyms |
Epocarbazolin-B
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Terminated | [1] | ||
| Company |
Bristol-Myers Squibb Co
|
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| Structure |
|
Download2D MOL |
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| Formula |
C22H27NO4
|
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| Canonical SMILES |
C1(OC1(CCC(C)C)C)c1c2[nH]c3c(c2cc(c1C)O)c(ccc3O)CO
|
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| CAS Number |
CAS 146935-39-9
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. J Antibiot (Tokyo). 1993 Jan;46(1):25-33. | ||||
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