Drug Information

Drug General Information
Drug ID
D09JRN
Former ID
DNC006817
Drug Name
3-(2-phenyl-2-(piperazin-1-yl)ethyl)benzonitrile
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528224]
Structure
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2D MOL

3D MOL
Formula
C19H21N3
Canonical SMILES
C1CN(CCN1)C(CC2=CC=CC(=C2)C#N)C3=CC=CC=C3
InChI
1S/C19H21N3/c20-15-17-6-4-5-16(13-17)14-19(18-7-2-1-3-8-18)22-11-9-21-10-12-22/h1-8,13,19,21H,9-12,14H2
InChIKey
JQQRBSOAFDAWGZ-UHFFFAOYSA-N
PubChem Compound ID
44414721
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [528224]
Sodium-dependent serotonin transporter Target Info Inhibitor [528224]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 528224Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. Epub 2006 Jun 5.N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.
Ref 528224Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. Epub 2006 Jun 5.N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.

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