Drug Information

Drug General Information
Drug ID
D09DWM
Former ID
DNC006576
Drug Name
Isobutyl-(4-methyl-benzyl)-piperidin-4-yl-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528048]
Structure
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2D MOL

3D MOL
Formula
C17H28N2
Canonical SMILES
CC1=CC=C(C=C1)CN(CC(C)C)C2CCNCC2
InChI
1S/C17H28N2/c1-14(2)12-19(17-8-10-18-11-9-17)13-16-6-4-15(3)5-7-16/h4-7,14,17-18H,8-13H2,1-3H3
InChIKey
GBWQTSFXTHVNTA-UHFFFAOYSA-N
PubChem Compound ID
44411213
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [528048]
Sodium-dependent serotonin transporter Target Info Inhibitor [528048]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 528048Bioorg Med Chem Lett. 2006 May 15;16(10):2714-8. Epub 2006 Feb 23.N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake.
Ref 528048Bioorg Med Chem Lett. 2006 May 15;16(10):2714-8. Epub 2006 Feb 23.N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake.

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