Drug Information

Drug General Information
Drug ID
D09DLN
Former ID
DNC012081
Drug Name
L-739749
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Terminated [545701]
Structure
Download
2D MOL

3D MOL
Formula
C24H41N3O6S2
Canonical SMILES
CCC(C)C(COC(CC1=CC=CC=C1)C(=O)NC(CCS(=O)(=O)C)C(=O)OC)N<br />CC(CS)N
InChI
1S/C24H41N3O6S2/c1-5-17(2)21(26-14-19(25)16-34)15-33-22(13-18-9-7-6-8-10-18)23(28)27-20(24(29)32-3)11-12-35(4,30)31/h6-10,17,19-22,26,34H,5,11-16,25H2,1-4H3,(H,27,28)/t17?,19-,20+,21-,22+/m1/s1
InChIKey
XDPAYLCHZOZGMW-DOKCZXGGSA-N
PubChem Compound ID
9893250
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [534466]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 545701Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004259)
Ref 534466J Med Chem. 1997 Sep 12;40(19):2971-90.Ras farnesyltransferase: a new therapeutic target.

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