Drug Information
Drug General Information | |||||
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Drug ID |
D09DIB
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Former ID |
DIB004058
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Drug Name |
RG-4929
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Synonyms |
R-4929; RO-5093151; 11-beta HSD inhibitor (type 2 diabetes), Roche; 11-beta hydroxysteroid dehydrogenase inhibitor (type 2 diabetes), Roche
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Drug Type |
Small molecular drug
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Indication | Metabolic disorders [ICD9: 270-279; ICD10:E70-E89] | Phase 2 | [523728] | ||
Company |
F Hoffmann-La Roche Ltd
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Structure |
Download2D MOL |
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Formula |
C23H27ClN2O2
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Canonical SMILES |
C1CN(CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4.Cl
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InChI |
1S/C23H26N2O2.ClH/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18;/h1-10,20H,11-17H2,(H,24,26,27);1H
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InChIKey |
XSOOSXRNMDUWEM-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Corticosteroid 11-beta-dehydrogenase, isozyme 1 | Target Info | Inhibitor | [551800] | |
NetPath Pathway | IL1 Signaling Pathway | ||||
FSH Signaling Pathway | |||||
PathWhiz Pathway | Steroidogenesis | ||||
Reactome | Glucocorticoid biosynthesis | ||||
References |
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