Drug Information
Drug General Information | |||||
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Drug ID |
D09CGE
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Former ID |
DNAP001682
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Drug Name |
Florbetapir F-18
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Synonyms |
Amyvid (TN)
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Drug Type |
Small molecular drug
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Indication | Diagnostic imaging [ICD9: 331; ICD10:G30, I73.9] | Approved | [532210] | ||
Company |
Avid Radiopharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C20H25FN2O3
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Canonical SMILES |
CNC1=CC=C(C=C1)C=CC2=CN=C(C=C2)OCCOCCOCCF
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InChI |
1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1
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InChIKey |
YNDIAUKFXKEXSV-CRYLGTRXSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | Modulator | [551871] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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