Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09BLB
|
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| Former ID |
DIB020340
|
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| Drug Name |
methylcarbamyl PAF
|
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| Synonyms |
methyl-carbamyl platelet-activating factor; mc-PAF
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C26H55N2O7P
|
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| InChI |
InChI=1S/C26H55N2O7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-32-23-25(35-26(29)27-2)24-34-36(30,31)33-22-20-28(3,4)5/h25H,6-24H2,1-5H3,(H-,27,29,30,31)/t25-/m1/s1
|
||||
| InChIKey |
FNFHZBKBDFRYHS-RUZDIDTESA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
10241144, 24895650, 26754998, 26754999, 29304643, 50110864, 57341013, 78679115, 92309698, 99300612, 99302130, 104046572, 104421324, 135082142, 135651517, 137324603, 162228688, 163133710, 163831827, 164758086, 184021200, 184568115, 231325247, 241175900, 242392779, 250136936, 252370953, 252455422, 252457458, 252464695
|
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| Target and Pathway | |||||
| Target(s) | Platelet-activating factor receptor | Target Info | Agonist | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Staphylococcus aureus infection | |||||
| NetPath Pathway | IL5 Signaling Pathway | ||||
| Leptin Signaling Pathway | |||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (q) signalling events | |||||
| Interferon gamma signaling | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Small Ligand GPCRs | |||||
| Interferon gamma signaling | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3427). | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 334). | ||||
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