Drug General Information
Drug ID
D09BGI
Former ID
DIB020099
Drug Name
JCF 109
Synonyms
JCF109; JCF-109
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538950]
Structure
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2D MOL

3D MOL

Formula
C24H27N3O4S
InChI
InChI=1S/C24H27N3O4S/c28-27(29)23-7-3-4-8-24(23)32(30,31)26-17-19-11-9-18(10-12-19)16-25-22-14-13-20-5-1-2-6-21(20)15-22/h1-8,13-15,18-19,25-26H,9-12,16-17H2/t18-,19-
InChIKey
BPBPTEVVRMSHTB-WGSAOQKQSA-N
PubChem Compound ID
Target and Pathway
Target(s) Neuropeptide Y receptor 5 Target Info Antagonist [526683]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538950(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1564).
Ref 526683Development and characterization of a highly selective neuropeptide Y Y5 receptor agonist radioligand: [125I][hPP1-17, Ala31, Aib32]NPY. Br J Pharmacol. 2003 Aug;139(7):1360-8.

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