| Drug General Information |
| Drug ID |
D08VFY
|
| Former ID |
DNC000275
|
| Drug Name |
Batimistat
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C23H31N3O4S2
|
| Target and Pathway |
| Target(s) |
ADAM 17 |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Notch signaling pathway
|
|
Alzheimer's disease
|
|
Epithelial cell signaling in Helicobacter pylori infection
|
|
PANTHER Pathway
|
Alzheimer disease-amyloid secretase pathway
|
|
Alzheimer disease-presenilin pathway
|
|
Notch signaling pathway
|
|
Pathway Interaction Database
|
ErbB4 signaling events
|
|
TNF receptor signaling pathway
|
|
p75(NTR)-mediated signaling
|
|
Reactome
|
Nuclear signaling by ERBB4
|
|
Collagen degradation
|
|
Regulated proteolysis of p75NTR
|
|
Activated NOTCH1 Transmits Signal to the Nucleus
|
|
Constitutive Signaling by NOTCH1 PEST Domain Mutants
|
|
Constitutive Signaling by NOTCH1 t(7
|
|
M1580_K2555) Translocation Mutant
|
|
Constitutive Signaling by NOTCH1 HD Domain Mutants
|
|
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
|
|
TNF signaling
|
|
Growth hormone receptor signaling
|
|
WikiPathways
|
Notch Signaling Pathway
|
|
Copper homeostasis
|
|
Notch Signaling Pathway
|
|
Growth hormone receptor signaling
|
|
BDNF signaling pathway
|
|
Alzheimers Disease
|
|
Signalling by NGF
|
|
Extrinsic Pathway for Apoptosis
|
| References |
| REF 1 | The secretases that cleave angiotensin converting enzyme and the amyloid precursor protein are distinct from tumour necrosis factor-alpha convertase. FEBS Lett. 1998 Jul 10;431(1):63-5. |
|---|
