Drug Information

Drug General Information
Drug ID
D08TRA
Former ID
DNC001240
Drug Name
RS-61980
Drug Type
Small molecular drug
Indication Discovery agent Investigative [537837]
Structure
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2D MOL

3D MOL
Formula
C12H9F3N2O2
CAS Number
CAS 108605-62-5
PubChem Compound ID
444960
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info Inhibitor [537837]
KEGG Pathway Pyrimidine metabolism
Metabolic pathways
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotides
References
Ref 537837Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide. Biochem Pharmacol. 1995 Sep 7;50(6):861-7.
Ref 537837Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide. Biochem Pharmacol. 1995 Sep 7;50(6):861-7.

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