TTD | Drug: D08QIR

Drug General Information
Drug ID	D08QIR
Former ID	DIB004693
Drug Name	H2S-releasing latanoprost
Synonyms	ACS-67; H2S-releasing latanoprost (ocular disease); H2S-releasing latanoprost (ocular disease), CTG Pharma
Indication	Ocular disease [ICD10:H00-H59]		Investigative	[543781]
Company	CTG Pharma Srl
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1c(=S)ssc1c1ccc(OC(=O)CCC/C=C\C[C@@H]2[C@H]([C@@H](C[C<br />@@H]2O)O)CC[C@H](CCc2ccccc2)O)cc1
Target and Pathway
Target(s)	Prostaglandin F2-alpha receptor	Target Info	Modulator	[543781]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Prostanoid ligand receptors
Reactome	G alpha (q) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 543781	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 344).
Ref 543781	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 344).

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Drug Information