Drug Information
Drug General Information | |||||
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Drug ID |
D08PBB
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Former ID |
DNC000854
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Drug Name |
L-694,458
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Drug Type |
Small molecular drug
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Indication | Cystic fibrosis [ICD9: 277; ICD10:E84] | Phase 2 | [551850] | ||
Structure |
Download2D MOL |
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Formula |
C31H40N4O6
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Canonical SMILES |
CCCC(C1=CC2=C(C=C1)OCO2)NC(=O)N3C(C(C3=O)(CC)CC)OC4=CC=<br />C(C=C4)C(=O)N5CCN(CC5)C
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InChI |
1S/C31H40N4O6/c1-5-8-24(22-11-14-25-26(19-22)40-20-39-25)32-30(38)35-28(37)31(6-2,7-3)29(35)41-23-12-9-21(10-13-23)27(36)34-17-15-33(4)16-18-34/h9-14,19,24,29H,5-8,15-18,20H2,1-4H3,(H,32,38)/t24-,29+/m1/s1
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InChIKey |
ZSDCIRYNTCVTMF-GIGWZHCTSA-N
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CAS Number |
CAS 157341-41-8
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PubChem Compound ID | |||||
PubChem Substance ID |
10258824, 14812969, 14837631, 33501323, 76570568, 103284927, 103961532, 104426838, 126671449, 134339075, 134340163, 135154870, 142336332, 152258908, 160647754, 160832438, 162797666, 163397633, 163844255, 180100906, 184527598, 185972329, 189659308, 198958258, 204429446, 223660457, 232251389, 244216908, 251963056, 252504726
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Target and Pathway | |||||
Target(s) | Leukocyte elastase | Target Info | Inhibitor | [535494] | |
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | ||||
C-MYB transcription factor network | |||||
References |
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