Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08OUV
|
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| Former ID |
DIB012797
|
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| Drug Name |
CHF-4227
|
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| Synonyms |
CHF-3316; CHF-4056; SERMs, Chiesi; Selective estrogen receptor modulators, Chiesi; CHF-3316.01
|
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| Drug Type |
Small molecular drug
|
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| Indication | Osteoporosis [ICD9: 733.0, V07.4; ICD10:M80-M81, Z79.890] | Phase 1 | [547486] | ||
| Company |
Chiesi Farmaceutici SpA
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C30H33NO4
|
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| Canonical SMILES |
C1(=C(COc2c1ccc(c2)O)c1ccc(cc1)OC)Cc1ccc(cc1)OCCN1CCCCC<br />1.Cl
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Modulator | [526427] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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