Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08OUU
|
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| Former ID |
DIB013260
|
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| Drug Name |
Genevx
|
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| Synonyms |
Ad5-VEGF145; Restenosis therapy, Collateral; VEGF gene therapy, Collateral
|
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| Indication | Angina pectoris [ICD9: 413; ICD10:I20] | Terminated | [1] | ||
| Company |
Collateral Therapeutics Inc
|
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| Target and Pathway | |||||
| Target(s) | VEGF receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| Cytokine-cytokine receptor interaction | |||||
| HIF-1 signaling pathway | |||||
| Endocytosis | |||||
| PI3K-Akt signaling pathway | |||||
| Focal adhesion | |||||
| Transcriptional misregulation in cancer | |||||
| Rheumatoid arthritis | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013170) | ||||
| REF 2 | Vascular Endothelial Growth Factor Gene Therapy Increases Survival, Promotes Lung Angiogenesis, and Prevents Alveolar Damage in Hyperoxia-Induced Lung Injury. Circulation. 2005; 112: 2477-2486. | ||||
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