Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08NWC
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| Former ID |
DAP001279
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| Drug Name |
Peginterferon alfa-2b
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| Synonyms |
PegIntron; Peg Intron (TN); Pegintron (TN); Peginterferon alfa-2b (INN); Peginterferon alfa-2b (generical recombination); Peginterferon alfa-2b (generical recombination) (JAN)
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| Therapeutic Class |
Antiviral Agents
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| Company |
Schering-Plough
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| CAS Number |
CAS 99210-65-8
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| PubChem Substance ID | |||||
| SuperDrug ATC ID |
L03AB10
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| Target and Pathway | |||||
| Target(s) | Interferon alpha 2 ligand | Target Info | Modulator | [556264] | |
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| Regulation of autophagy | |||||
| PI3K-Akt signaling pathway | |||||
| Toll-like receptor signaling pathway | |||||
| RIG-I-like receptor signaling pathway | |||||
| Cytosolic DNA-sensing pathway | |||||
| Jak-STAT signaling pathway | |||||
| Natural killer cell mediated cytotoxicity | |||||
| Tuberculosis | |||||
| Hepatitis C | |||||
| Hepatitis B | |||||
| Measles | |||||
| Influenza A | |||||
| Herpes simplex infection | |||||
| Autoimmune thyroid disease | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | Downstream signaling in naï | ||||
| References | |||||
| Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| Ref 542487 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7462). | ||||
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