TTD | Drug: D08LQD

Drug General Information
Drug ID	D08LQD
Former ID	DIB002843
Drug Name	RESEQUINIL
Synonyms	AVE-3933; SX-3933; Resequinil < Prop INN >; 5-(3-Methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one
Drug Type	Small molecular drug
Indication	Epilepsy [ICD10:G40]		Discontinued in Phase 2	[546863]
Structure		Download 2D MOL 3D MOL
Formula	C18H14N4O3
Canonical SMILES	COc1cccc(c1)c2nccc3NC(=O)C(=Cc23)c4noc(C)n4
InChI	1S/C18H14N4O3/c1-10-20-17(22-25-10)14-9-13-15(21-18(14)23)6-7-19-16(13)11-4-3-5-12(8-11)24-2/h3-9H,1-2H3,(H,21,23)
InChIKey	JQOFKKWHXGQABB-UHFFFAOYSA-N
PubChem Compound ID	9862502
Target and Pathway
Target(s)	GABA A receptor	Target Info	Agonist	[550144]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 546863	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010724)
Ref 550144	WO patent application no. 2010,0024,51, Naphthyridin derivatives.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information