Drug Information
Drug General Information | |||||
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Drug ID |
D08KIB
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Former ID |
DIB012830
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Drug Name |
SAR-114137
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Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Phase 1 | [532135] | ||
Company |
Sanofi
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Structure |
Download2D MOL |
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Target and Pathway | |||||
Target(s) | Cathepsin S | Target Info | Inhibitor | [532135] | |
Cathepsin K | Target Info | Inhibitor | [532135] | ||
Reactome | Endosomal/Vacuolar pathway | ||||
Degradation of the extracellular matrix | |||||
Trafficking and processing of endosomal TLR | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
Activation of Matrix Metalloproteinases | |||||
MHC class II antigen presentation | |||||
References |
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