TTD | Drug: D08HPL

Drug General Information
Drug ID	D08HPL
Former ID	DIB018609
Drug Name	3S,4R-293B
Synonyms	chromanol 239B
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526219]
Structure		Download 2D MOL
Formula	C15H20N2O4S
InChI	InChI=1S/C15H20N2O4S/c1-5-22(19,20)17(4)13-11-8-10(9-16)6-7-12(11)21-15(2,3)14(13)18/h6-8,13-14,18H,5H2,1-4H3/t13-,14+/m1/s1
InChIKey	HVSJHHXUORMCGK-KGLIPLIRSA-N
PubChem Compound ID	6604863
PubChem Substance ID	11114072, 11114073, 11646524, 15396662, 43224601, 52629455, 103223570, 103996437, 114638131, 135697640, 135698551, 230235378, 252166811
Target and Pathway
Target(s)	Potassium voltage-gated channel subfamily KQT member 1	Target Info	Blocker (channel blocker)	[526219]
KEGG Pathway	Adrenergic signaling in cardiomyocytes
	Cholinergic synapse
	Gastric acid secretion
	Pancreatic secretion
	Protein digestion and absorption
	Vibrio cholerae infection
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	Voltage gated Potassium channels
WikiPathways	SIDS Susceptibility Pathways
	Potassium Channels
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	TarBasePathway
References
Ref 526219	A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B. Br J Pharmacol. 2001 Dec;134(8):1647-54.
Ref 526219	A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B. Br J Pharmacol. 2001 Dec;134(8):1647-54.

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Drug Information