Drug Information
Drug General Information | |||||
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Drug ID |
D08HFW
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Former ID |
DCL000657
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Drug Name |
TAK-901
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Drug Type |
Small molecular drug
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Indication | Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] | Phase 1 | [548836] | ||
Company |
Takeda
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Structure |
Download2D MOL |
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Formula |
C28H32N4O3S
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Canonical SMILES |
CCS(=O)(=O)C1=CC=CC(=C1)C2=CC(=C(C3=C2C4=CC(=CN=C4N3)C)<br />C)C(=O)NC5CCN(CC5)C
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InChI |
1S/C28H32N4O3S/c1-5-36(34,35)21-8-6-7-19(14-21)23-15-22(28(33)30-20-9-11-32(4)12-10-20)18(3)26-25(23)24-13-17(2)16-29-27(24)31-26/h6-8,13-16,20H,5,9-12H2,1-4H3,(H,29,31)(H,30,33)
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InChIKey |
WKDACQVEJIVHMZ-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
24772915, 28725871, 40658123, 124976958, 131549293, 136340315, 136349569, 136367700, 139700564, 152258406, 160647243, 162011362, 162038103, 162202640, 164020967, 164194000, 172914487, 174006378, 174531561, 185979181, 202559448, 223388595, 223704783, 224282669, 226944802, 242060029, 249254536, 251910775, 252109875, 252165326, 252216369
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Target and Pathway | |||||
Target(s) | Aurora kinase B | Target Info | Inhibitor | [551717] | |
Pathway Interaction Database | Aurora B signaling | ||||
Signaling by Aurora kinases | |||||
Aurora C signaling | |||||
FOXM1 transcription factor network | |||||
Aurora A signaling | |||||
References |
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