Drug Information
Drug General Information | |||||
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Drug ID |
D08GKL
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Former ID |
DNC007312
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Drug Name |
6-iodo-4'-methylaminoflavone
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [527855] | ||
Structure |
Download2D MOL |
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Formula |
C16H12INO2
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Canonical SMILES |
CNC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)I
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InChI |
1S/C16H12INO2/c1-18-12-5-2-10(3-6-12)16-9-14(19)13-8-11(17)4-7-15(13)20-16/h2-9,18H,1H3
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InChIKey |
QIZWRTNISFPGTO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527855] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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