Drug Information

Drug General Information
Drug ID
D07ZTG
Former ID
DNC012074
Drug Name
L-739750
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542933]
Structure
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2D MOL

3D MOL
Formula
C23H39N3O6S2
InChI
InChI=1S/C23H39N3O6S2/c1-4-16(2)20(25-13-18(24)15-33)14-32-21(12-17-8-6-5-7-9-17)22(27)26-19(23(28)29)10-11-34(3,30)31/h5-9,16,18-21,25,33H,4,10-15,24H2,1-3H3,(H,26,27)(H,28,29)/t16-,18+,19-,20+,21-/m0/s1
InChIKey
SIEXHGZWGJLLAC-OSTWSGHESA-N
PubChem Compound ID
5287548
PubChem Substance ID
7885475, 8011924, 11041300, 14762758, 39320155, 74453333, 113869925, 129239741, 228808794, 249565710
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [534466]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 542933(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8030).
Ref 534466J Med Chem. 1997 Sep 12;40(19):2971-90.Ras farnesyltransferase: a new therapeutic target.

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