Drug Information

Drug General Information
Drug ID
D07YEK
Former ID
DCL000181
Drug Name
NV-52
Indication Inflammatory bowel disease [ICD9: 555, 556; ICD10:K50, K51] Phase 1 [547537]
Company
Novogen
Target and Pathway
Target(s) Thromboxane-A synthase Target Info Inhibitor [536468], [536703]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
References
Ref 547537Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017139)
Ref 536468Nv-52: a novel thromboxane synthase inhibitor for the treatment of inflammatory bowel disease. Expert Opin Investig Drugs. 2007 Aug;16(8):1255-66.
Ref 536703Phase Ib single- and multiple-dose pharmacokinetic study of oral NV-52 in healthy volunteers. Drugs R D. 2008;9(3):159-66.

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