Drug Information

Drug General Information
Drug ID
D07YCR
Former ID
DIB003990
Drug Name
S-16020-2
Synonyms
N-[2-(Dimethylamino)ethyl]-9-hydroxy-5,6-dimethyl-6H-pyrido[4,3-b]carbazole-1-carboxamide dihydrochloride
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Discontinued in Phase 2 [545682]
Structure
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2D MOL

3D MOL
Formula
C22H26Cl2N4O2
Canonical SMILES
CC1=C2C(=CC3=C1C=CN=C3C(=O)NCCN(C)C)C4=C(N2C)C=CC(=C4)O<br />.Cl.Cl
InChI
1S/C22H24N4O2.2ClH/c1-13-15-7-8-23-20(22(28)24-9-10-25(2)3)17(15)12-18-16-11-14(27)5-6-19(16)26(4)21(13)18;;/h5-8,11-12,27H,9-10H2,1-4H3,(H,24,28);2*1H
InChIKey
DSJBVXJNKBKZSB-UHFFFAOYSA-N
CAS Number
CAS 156055-46-8
PubChem Compound ID
177329
PubChem Substance ID
10258591, 12014877, 14930938, 33500784, 79312657, 104426303, 135154833
Target and Pathway
Target(s) Toposisomerase-1 Target Info Modulator
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 545682Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004159)

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