Drug Information

Drug General Information
Drug ID
D07UXP
Former ID
DAP000999
Drug Name
Cinoxacin
Synonyms
Cinobac; Cinobactin; Cinoxacine; Cinoxacino; Cinoxacinum; Cinx; Clinoxacin; Uronorm; Azolinic Acid; C 8645; Lilly 64716; TNP00246; Cinobac (TN); Cinoxacine [INN-French]; Cinoxacino [INN-Spanish]; Cinoxacinum [INN-Latin]; Cinoxacin (JAN/USP/INN); Cinoxacin [USAN:BAN:INN:JAN]; 1-Ethyl-1,4-dihydro-4-oxo(1,3)dioxolo(4,5-g)cinnoline-3-carboxylic acid; 1-Ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid; 1-Ethyl-4-oxo-1,4-dihydro[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid; 1-Ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid; 1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
Drug Type
Small molecular drug
Indication Urinary tract infections [ICD9: 599; ICD10:N39.0] Approved [538497], [551871]
Therapeutic Class
Antiinfective Agents
Structure
Download
2D MOL

3D MOL
Formula
C12H10N2O5
Canonical SMILES
CCN1C2=CC3=C(C=C2C(=O)C(=N1)C(=O)O)OCO3
InChI
1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)
InChIKey
VDUWPHTZYNWKRN-UHFFFAOYSA-N
CAS Number
CAS 28657-80-9
PubChem Compound ID
2762
PubChem Substance ID
10252, 453513, 640098, 855948, 4816526, 7847937, 7978949, 8149259, 8151783, 10321339, 11110995, 11110996, 11110997, 11335493, 11360732, 11363046, 11365608, 11368170, 11371363, 11373957, 11376332, 11461704, 11466808, 11467928, 11484096, 11486535, 11488386, 11490168, 11492104, 11493966, 12015380, 15490737, 17404872, 24278343, 26611663, 26679855, 26747051, 26747052, 29221917, 46507547, 47216687, 47291046, 47440155, 47810655, 48035014, 48035015, 48110366, 48259141, 48334399, 48415782
SuperDrug ATC ID
J01MB06
SuperDrug CAS ID
cas=028657809
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [534884]
References
Ref 538497FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018067.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 534884The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. J Pharmacol Exp Ther. 1999 Aug;290(2):672-7.

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