Drug Information
Drug General Information | |||||
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Drug ID |
D07UHX
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Former ID |
DIB005256
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Drug Name |
9-AMINOCAMPTOTHECIN
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Synonyms |
IDEC-132; (S)-10-Amino-4-ethyl-4-hydroxy-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione; 9-Amino-20(S)-camptothecin
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Drug Type |
Small molecular drug
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Indication | Acquired immune deficiency syndrome [ICD9: 42; ICD10:B20] | Phase 2 | [521423] | ||
Structure |
Download2D MOL |
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Formula |
C20H17N3O4
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Canonical SMILES |
CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)N)<br />O
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InChI |
1S/C20H17N3O4/c1-2-20(26)13-7-16-17-10(6-11-14(21)4-3-5-15(11)22-17)8-23(16)18(24)12(13)9-27-19(20)25/h3-7,26H,2,8-9,21H2,1H3/t20-/m0/s1
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InChIKey |
FUXVKZWTXQUGMW-FQEVSTJZSA-N
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CAS Number |
CAS 91421-43-1
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PubChem Compound ID | |||||
PubChem Substance ID |
483848, 600881, 8195177, 11408968, 12014702, 14876953, 14876954, 26725257, 43128571, 50028358, 57318699, 77695393, 87560557, 96023346, 99373552, 99432308, 103073229, 103082936, 103170467, 103910998, 103922005, 104352855, 117586313, 119525751, 124796287, 124953919, 127347071, 127903358, 135030378, 137138142, 142371086, 152036014, 152227690, 160809182, 162179182, 162937855, 163374696, 164758081, 170559265, 172860100, 174531450, 178115205, 179151428, 184538696, 188900245, 198973567, 223445740, 223603491, 225031198, 226414396
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Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [525970] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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