Drug Information
Drug General Information | |||||
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Drug ID |
D07SAQ
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Former ID |
DIB002684
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Drug Name |
Tie-2 inhibitors
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Synonyms |
Tek inhibitors (cancer), AstraZeneca; Tie-2 inhibitors (cancer); Tie-2 inhibitors (cancer), AstraZeneca
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [552059] | ||
Company |
AstraZeneca plc
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Structure |
Download2D MOL |
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Canonical SMILES |
n1cnc2c(c1N)nc(s2)c1n(cnc1c1ccccc1)Cc1ccccc1N1CCOCC1
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Target and Pathway | |||||
Target(s) | Angiopoietin 1 receptor | Target Info | Inhibitor | [543511] | |
NetPath Pathway | Wnt Signaling Pathway | ||||
PANTHER Pathway | Angiogenesis | ||||
Pathway Interaction Database | Angiopoietin receptor Tie2-mediated signaling | ||||
SHP2 signaling | |||||
Reactome | Tie2 Signaling | ||||
RAF/MAP kinase cascade | |||||
References |
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