Drug Information
Drug General Information | |||||
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Drug ID |
D07PSL
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Former ID |
DIB013734
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Drug Name |
PLX7486
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Indication | Pancreatic cancer [ICD9: 140-199, 140-229, 157, 210-229; ICD10:C25] | Phase 1 | [549504] | ||
Company |
Daiichi sankyo
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Target and Pathway | |||||
Target(s) | Neurotrophic tyrosine kinase receptor 1 | Target Info | Inhibitor | [550497] | |
Macrophage colony-stimulating factor receptor | Target Info | Inhibitor | [550497] | ||
KEGG Pathway | MAPK signaling pathway | ||||
Endocytosis | |||||
Apoptosis | |||||
Neurotrophin signaling pathway | |||||
Inflammatory mediator regulation of TRP channels | |||||
Pathways in cancer | |||||
Transcriptional misregulation in cancer | |||||
Thyroid cancer | |||||
Central carbon metabolism in cancerhsa04060:Cytokine-cytokine receptor interaction | |||||
PI3K-Akt signaling pathway | |||||
Jak-STAT signaling pathway | |||||
Hematopoietic cell lineage | |||||
Pathway Interaction Database | Neurotrophic factor-mediated Trk receptor signaling | ||||
References |
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