Drug Information

Drug General Information
Drug ID
D07PNM
Former ID
DIB020337
Drug Name
methyl isocyanate
Synonyms
isocyanatomethane; methyl carbonimide; isocyanic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541441]
Structure
Download
2D MOL
Formula
C2H3NO
InChI
InChI=1S/C2H3NO/c1-3-2-4/h1H3
InChIKey
HAMGRBXTJNITHG-UHFFFAOYSA-N
PubChem Compound ID
12228
PubChem Substance ID
110287, 589868, 3155087, 7643139, 8159109, 10530597, 14793619, 17388916, 29280474, 48417653, 48421615, 48423680, 48425294, 49855636, 51075236, 52893694, 53788884, 57327467, 57568205, 57642282, 88829103, 92741967, 104328392, 119507770, 124406518, 124890416, 125570785, 126689675, 127326169, 127326170, 127326171, 127326172, 127326173, 127326174, 127795881, 127828353, 128032755, 131321534, 131498543, 134977521, 135158899, 135584707, 137001545, 142045549, 142291579, 144208258, 152137114, 160999230, 162238955, 162630919
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [529822]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541441(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6290).
Ref 529822Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases. FASEB J. 2009 Apr;23(4):1102-14.

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