TTD | Drug: D07JMB

Drug General Information
Drug ID	D07JMB
Former ID	DNC007256
Drug Name	8-aza-11-deoxyprostaglandin E1
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527306]
Structure		Download 2D MOL 3D MOL
Formula	C19H33NO4
Canonical SMILES	CCCCCC(C=CC1CCC(=O)N1CCCCCCC(=O)O)O
InChI	1S/C19H33NO4/c1-2-3-6-9-17(21)13-11-16-12-14-18(22)20(16)15-8-5-4-7-10-19(23)24/h11,13,16-17,21H,2-10,12,14-15H2,1H3,(H,23,24)/b13-11+/t16-,17-/m0/s1
InChIKey	XOPMUDZOEKPBQZ-NSNJOPQOSA-N
PubChem Compound ID	44289922
Target and Pathway
Target(s)	Prostaglandin E2 receptor, EP4 subtype	Target Info	Inhibitor	[527306]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Inflammatory mediator regulation of TRP channels
	Renin secretion
	Pathways in cancer
NetPath Pathway	FSH Signaling Pathway
	IL2 Signaling Pathway
	IL4 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
Reactome	Prostanoid ligand receptors
Reactome	G alpha (s) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Vitamin D Receptor Pathway
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527306	J Med Chem. 2004 Dec 2;47(25):6124-7.Lactams as EP4 prostanoid receptor agonists. 3. Discovery of N-ethylbenzoic acid 2-pyrrolidinones as subtype selective agents.
Ref 527306	J Med Chem. 2004 Dec 2;47(25):6124-7.Lactams as EP4 prostanoid receptor agonists. 3. Discovery of N-ethylbenzoic acid 2-pyrrolidinones as subtype selective agents.

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Drug Information