Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D07FHW
|
||||
Former ID |
DNC014069
|
||||
Drug Name |
PF-915275
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Non-insulin dependent diabetes [ICD10:E11.9] | Discontinued in Phase 1 | [548447] | ||
Structure |
Download2D MOL |
||||
Formula |
C18H14N4O2S
|
||||
Canonical SMILES |
C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N
|
||||
InChI |
1S/C18H14N4O2S/c19-12-13-4-6-14(7-5-13)15-8-10-16(11-9-15)25(23,24)22-18-3-1-2-17(20)21-18/h1-11H,(H3,20,21,22)
|
||||
InChIKey |
ZESFDAKNYJQYKO-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Corticosteroid 11-beta-dehydrogenase, isozyme 1 | Target Info | Inhibitor | [530170] | |
NetPath Pathway | IL1 Signaling Pathway | ||||
FSH Signaling Pathway | |||||
PathWhiz Pathway | Steroidogenesis | ||||
Reactome | Glucocorticoid biosynthesis | ||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.